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ITEM CODE: CW_SHC_2003_0011
Medical Biofilm Microbiology: The Role of Microbial Biofilms in Disease, Chronic Infections, and Medical Device Failure
Author: Dr. J. William Costerton | view all products by this author

This product can also be purchased with the following package(s): 2003 Cytergy Courseware Subscription, Anti-Infective Medical Devices, Implants, and Coatings 2003, Biofilm Science in Healthcare and Medicine 2003.

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Price: $119.95

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Also available with purchase of this courseware:

  • Downloadable print copy of presentation slides (Adobe PDF)
  • Glossary of key terms
  • Bibliography of related publications
  • List of online resources
  • Technical support from instructor (at a discounted consulting rate available only through Cytergy)
Product Description

The Centers for Disease Control and the National Institutes of Health estimate that 65% to 80% of all chronic infections can be attributed to microbial biofilms. Many of these chronic infections are caused by organisms such as Candida albicans, Pseudomonas aerugionsa, E. coli, Staphylococcus epidermidis, and Staphylococcus aureus.

Renowned microbiologist Dr. J. William "Bill" Costerton, the modern day father of biofilm microbiology and Director of the Center for Biofilm Engineering, discusses the role that biofilms play in medical contexts. Featured in this short course are animated and sound discussions of biofilm microbiology, medical device infections, chronic diseases, new methods, and specific case studies.

Medical Biofilm Microbiology outlines new concepts in infection prevention, treatment, and control, including important analyses of biofilm-host response interactions, antibiotic and host defense susceptibility, and the differences in biofilm growth on tissues vs. implanted foreign surfaces.

Dr. Costerton presents a frank discussion of the failure of conventional microbiology to adequately address biofilm diseases and protect human health, but offers innovative solutions and presentation of emerging diagnostic technologies that provide the foundation for assessing and treating biofilm infections.

Length: 50 Minutes

Outline

TITLE: Medical Biofilm Microbiology: The Role of Microbial Biofilms in Disease, Chronic Infections, and Medical Device Failure

AUTHOR: Dr. Bill Costerton

CASE STUDIES IN CHRONIC INFECTIONS:

  • Endocardial Pacemakers
  • Hickman Catheters
  • Bacterial Endocarditis
  • Staphylococcus Osteomyelitis
  • Human Tricuspid Valve Vegetation
  • Urinary Catheters
  • Cystic Fibrosis
  • Middle Ear Infections
  • Chronic Prostatitis
  • Toxic Shock Syndrome
  • Mechanical Heart Valves
  • Acetubular Cup Failure
  • Vascular Graft Infections
  • Esophegal Mechanical Valves

TREATMENT APPLICATIONS:

  • Vaccine Development
  • Antimicrobial Surfaces for Biomaterials
  • Antibiotic Susceptibility
  • Host Defense Susceptibility
  • Ultrasound-Mediated Drug Release from a Biomaterial Surface
  • Cell signaling and signal disruption
  • Cytokines in inflammation and disease: cell- and humoral-mediated immunity
  • Relationships between biofilms, antibiotics, antibodies, and phagocytes
  • Biofilm antigens and in-vivo monitoring of biofilm infections

ANALYSIS TECHNIQUES:

  • Confocal Scanning Laser Microscopy
  • Scanning Electron Microscopy
  • Transmission Electron Microscopy
  • Fluorescence In-Situ Hybridization (FISH)
  • ELISA
  • Animal Models for Biofilm Growth and Host Response
  • Disadvantages of subculturing, swab and scrape sampling, and colony plating

Author Biography

Dr. J. William “Bill” Costerton is the Director of Montana State University's world-renown Center for Biofilm Engineering.

Dr. Costerton obtained his B.S. and M.S. degrees in Bacteriology and Immunology from the University of British Columbia, and his doctorate from the University of Western Ontario. He pursued post-doctoral training at London’s Cambridge University.

In the late 1970s while serving as Professor of Biology at the University of Calgary, his research on microbial biofilms shattered conventional wisdom in the discipline of bacterial microbiology and gained him the respect of scientists around the world. He has since remained at the forefront of research in the still emerging field of biofilms.

As one of the world’s top 100 most-cited authors in microbiology, Dr. Costerton has helped educate healthcare professionals about the structure, behavior, and antibiotic resistance of bacteria that form biofilm colonies. His research and biological patents help save lives and increase the success of therapies designed to control chronic infections caused by bacterial films residing on medical implants or human tissue. The usefulness of Dr. Costerton’s biofilm discoveries are not limited to the healthcare industry. Petroleum, agricultural, and water storage companies have also benefited from his groundbreaking work. At present he continues his research and publication projects as Director of the Center for Biofilm Engineering at Montana State University in Bozeman.

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